The reversal of the bacteriostatic action of streptomycin by urea.
نویسندگان
چکیده
The bacteriostatic effect of streptomycin on E. coli and M. luberculosis 607 and H37RV can be antagonized by a number of purines and pyrimidines. These include xanthine, uric acid, allantoin, alloxan, and parabanic acid. It seemed possible that these compounds might give rise to urea. If such were the case, urea should antagonize the effect of streptomycin and the effect should be demonstrable sooner than when the urea precursors are used. These two conditions were fulfilled and the table shows the reversal
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 172 2 شماره
صفحات -
تاریخ انتشار 1948